Preparation and characterization of chitosan and trimethyl-chitosanmodified poly-(ε-caprolactone) nanoparticles as DNA carriers

Preparation and Characterization of Nanoparticles Using Poly(N-isopropylacrylamide)- Poly(ε-caprolactone) and Poly(ethylene glycol)-Poly(ε-caprolactone) Block Copolymers with Thermosensitive Function

Thermosensitive nanoparticles were prepared via the self-assembly of two different poly(ε-caprolactone)-based block copolymers of poly(N-isopropylacrylamide)-b-poly(ε-caprolactone) (PNPCL) and poly(ethylene glycol)-b-poly(ε-caprolactone) (PEGCL). The self-aggregation and thermosensitive behaviors of the mixed nanoparticles were investigated using 1H-NMR, turbidimetry, differential scanning micr...

preparation and characterization of poly(e-caprolactone)–poly(ethylene glycol) – poly(e-caprolactone) nanoparticles for sustained release of tamoxifen

Preparation and Evaluation of Poly (ε-caprolactone) Nanoparticles-in- Microparticles by W/O/W Emulsion Method

Objective(s) Theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. It is used both as a prophylactic drug and to prevent acute exacerbations of asthma. The aim of study was to formulate and evaluate effect of the microencapsulation of theophylline loaded nanoparticles on the reduction of burst release. Materials and Me...

Preparation and characterization of polylactide/poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) hybrid fibers for potential application in bone tissue engineering

The aim of this study was to develop a kind of osteogenic biodegradable composite graft consisting of human placenta-derived mesenchymal stem cell (hPMSC) material for site-specific repair of bone defects and attenuation of clinical symptoms. The novel nano- to micro-structured biodegradable hybrid fibers were prepared by electrospinning. The characteristics of the hybrid membranes were investi...

Preparation and Evaluation of Vancomycin-Loaded N-trimethyl Chitosan Nanoparticles

Chronic intracellular infections caused by drug-resistant pathogens pose a challenge to the treatment of chronic osteomyelitis. Such treatment requires an intracellular delivery system for the sustained release of antibiotics such as vancomycin (VCM), which is an antibiotic of last resort used against many clinically resistant bacteria. In this work, we report VCM-loaded N-trimethyl chitosan (T...